Breeding is the backbone of Mewgenics. Winning a single run feels good, but building strong bloodlines is what actually pushes long-term progress. Every kitten you raise shapes future generations, so smart breeding decisions matter from the very first in-game week.

This guide explains how cat breeding works, which house stats matter most, how inheritance really functions, and how to avoid common mistakes like inbreeding or wasting good genetics.
How Cat Breeding Works in Mewgenics
Cats can breed when compatible cats stay together in the same room overnight. Breeding checks happen when you end the day, and kittens appear the next morning if conditions allow it.

You cannot directly choose which two cats breed. Instead, you influence outcomes by controlling room setup, furniture bonuses, and which cats share space.
Key rules to remember:
- Cats must be compatible by gender and sexuality.
- Breeding may not happen every night.
- Cats can also fight, get injured, or die overnight.
- Kittens cannot go on adventures until their second day.
House vs Room Stats: How Breeding Works in Mewgenics
Your house stats directly shape breeding quality. Furniture placement and cleanliness determine these values.
Appeal (Whole House)
- Appeal controls the quality of stray cats that appear each day. Higher Appeal means better base stats on new arrivals.
- Priority: Upgrade this early. Better strays create better bloodlines.
Comfort (Per Room)
- Comfort affects how often cats breed or fight. Higher Comfort increases breeding chances and reduces chaos.
Stimulation (Per Room)
- Stimulation determines inheritance quality. High Stimulation increases the chance kittens inherit the higher base stats and abilities from parents.
- This is the most important stat for serious breeding.
Health (Per Room)
- Health affects disease spread, healing, and lifespan. Clean poop and remove corpses to keep Health stable.
Mutation (Per Room)
- Mutation adds a chance for random mutations. Mutations can break stat caps but may come with drawbacks.
How Base Stats Affect Cat Breeding in Mewgenics
Kittens inherit base stats only, not the boosted stats gained from leveling or gear.
If a parent has:
- Base Strength: 6
- Current Strength after leveling: 10
The kitten can only inherit 6, not 10.
Because of this:
- Always check base stats once unlocked
- Value cats with multiple base stats at 6 or higher
- Do not keep weak cats just because they performed well in one run
Why You Should Unlock Tink’s Tools Early in Mewgenics
Sending kittens to Tink unlocks essential breeding information. This is not optional if you want efficient progress.

Tink lets you see:
- Base stats vs current stats
- Sexuality and gender
- Libido and aggression
- Inbreeding status
- Family trees
Donate weak kittens early to unlock these features faster. This gives you full visibility into which cats deserve a place in your breeding pool.
Cull Weak Bloodlines Without Guilt
Not every cat deserves a future.
A practical early-game rule:
- If a cat has no base stat at 6 or higher, let them go
Later in the game, raise standards:
- Keep cats with multiple 6+ base stats
- Prioritize cats with a single stat at 7
- Favor clean mutation profiles with minimal downsides
Donating weak kittens improves long-term breeding efficiency.
Avoid Inbreeding at All Costs
Inbreeding leads to:
- Birth defects
- Weaker base stats
- Ugly mutation penalties
As soon as you unlock multiple rooms:
- Separate parents from offspring
- Split family lines across rooms
- Use attic or spare rooms for non-breeders
If a cat develops serious defects, send them to research NPCs or remove them from the gene pool.
Separate Breeders From Growers
Use room separation strategically:
- Main Room: High Stimulation + Comfort for elite breeders
- Secondary Room: Growing kittens and low-value cats
- Overflow Room: Donation and mutation experiments
This setup prevents accidents and keeps breeding focused on top-tier cats.
Mutations Can Break the Stat Ceiling
Base stats normally cap at 7. Mutations are the only way to exceed this limit.
Not all mutations are bad:
- Some add powerful stat boosts with minor tradeoffs
- Others synergize well with specific classes
Example:
A mutation that adds +2 Constitution but removes Dexterity works perfectly on Tanks or Fighters.
Always evaluate mutations based on class direction, not raw negatives.
Sexuality, Libido, and Relationships Matter
Cats have genders and sexualities that affect breeding:
- Same-gender cats cannot produce kittens
- Gay cats increase the chance of high-quality gay strays
- High libido increases breeding attempts
- Aggression increases fights
Affinities also matter:
- Cats that love each other breed more often
- Enemies fight instead of breeding
Use Tink’s data to control room chemistry.
Best Early-Game Breeding Strategy in Mewgenics
Follow this order for best results:
- Upgrade Appeal first to improve stray quality
- Unlock Tink’s stat tools as soon as possible
- Focus Stimulation and Comfort in one breeding room
- Cull weak kittens aggressively
- Separate family lines once extra rooms unlock
- Preserve strong mutations carefully
This approach builds stronger cats every generation instead of stalling progress.
Breeding in Mewgenics rewards patience and planning. You do not need perfect cats early, but you do need smart decisions. Every weak bloodline you remove and every strong base stat you preserve compounds power over time.
If you treat breeding as a long-term system instead of a random mechanic, the game opens up in a completely different way. Play Now!
