Best Weapons in Resident Evil Requiem (Best Loadout for Leon & Grace)

Resident Evil Requiem gives players two very different combat styles. Grace focuses on survival horror with limited weapons, while Leon handles the action-heavy sections with a full arsenal. Because resources are limited, choosing the right weapons early makes the game much easier, especially on higher difficulties.

In this guide, you will learn the best weapons in Resident Evil Requiem, which guns you should upgrade first, and the best loadout to carry during the main story.

Best Weapons for Leon in Resident Evil Requiem

Leon has access to the largest number of weapons in the game. However, only a few are worth upgrading during your first playthrough.

Below are the strongest weapons you should always keep in your inventory.

Silencer 9 – Best Handgun

Silencer 9 is the best pistol for most situations. It has strong damage, high accuracy, and a large magazine size, which makes it perfect for regular enemies. It also includes a suppressor, which helps avoid alerting nearby zombies.

Upgrade priority:

• Add-on Suppressor
• High-Capacity Magazine

This weapon should stay in your loadout for the entire game.

990-TAC – Best Shotgun

The 990-TAC is the strongest shotgun in the main story. It fires faster than pump shotguns and deals heavy damage at close range. It also has better stability and reload speed compared to earlier weapons.

Upgrade priority:

• Ceramic Coated Barrel
• Carbon Tube Extension

You should replace the starting shotgun as soon as this becomes available.

Marksman 1A – Best Rifle

Marksman 1A is the best rifle for the main story. It has faster firing speed, better reload time, and much larger ammo capacity than the Classic 70.

Because it can hold over 25 rounds, it works well for both long-range and mid-range fights.

Upgrade priority:

• Reinforced Bolt
• High-Capacity Mag

This rifle is one of the most useful weapons for boss fights.

Sitri REVO3 A1 – Best SMG

Sitri REVO3 A1 does less damage per shot, but its high fire rate makes it perfect for large groups of enemies.

Use this weapon when:

• Fighting hordes
• Defending narrow areas
• Saving shotgun ammo

Upgrade priority:

• Long Flash Guard
• High-Capacity Mag

This weapon becomes very useful in later chapters.

Requiem – Best Revolver

Requiem has the highest damage in the main story. Its ammo is rare, so you should save it for bosses and heavy enemies.

Upgrade priority:

• Ported Barrel
• Barrel Jacket

A fully upgraded Requiem can kill most enemies in one or two shots.

Best Weapons for Grace in Resident Evil Requiem

Grace has fewer weapons, so upgrades matter more.

Grace relies more on inventory upgrades and health boosts than weapons.

Important upgrades for Grace:

• Hip Pouch (more inventory slots)
• Steroids (increase health)
• Override Manual (more crafting resources)

These upgrades improve survival more than new weapons.

Best Loadout for First Playthrough

Use this setup for the easiest experience.

This loadout gives you damage, range, and ammo balance.

Best Upgrades to Buy First in Resident Evil Requiem

Do not waste credits early. Buy these first:

• Case Upgrade (more inventory)
• Body Armor
• Ammo Capacity upgrades
• Shotgun upgrades
• Rifle upgrades

Inventory space is more important than damage early in the game.

The best weapons in Resident Evil Requiem are the ones that balance power, ammo capacity, and upgrade potential. Silencer 9, 990-TAC, Marksman 1A, Sitri REVO3 A1, and Requiem form the best loadout for most players.

If you upgrade these weapons first, the game becomes much easier even on higher difficulty. Play Now!